Genetic screens to identify loci affecting phase of entrainment of Eclosion and Locomotor activity rhythm in *Drosophila melanogaster*

Abstract

Circadian rhythms are cyclic behavioural and physiological rhythms exhibited by a variety of organisms spanning from single celled bacteria to mammals. These rhythms provide adaptive advantage to organisms and are driven by their internal biological clock, which initiate, control and monitor various physiological processes. Circadian rhythms maintain a fixed periodicity and a stable, reproducible phase relationship with external stimuli. The main objective of this study is to find loci which might be responsible for differential phase of entrainment of eclosion and locomotor activity rhythm in Drosophila melanogaster by screening for abnormal circadian activity.